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Updated: Jun 5, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Diagnostics and epidemiology in ventilator-associated pneumonia
Andrew F Shorr1, Chee M Chan, Marya D Zilberberg
1Pulmonary and Critical Care Medicine, Room 2A-68D, Washington Hospital Center, 110 Irving Street NW, Washington, DC 20010, USA. afshorr@dnamail.com
Ventilator-associated pneumonia (VAP) is a common ICU complication. Understanding VAP diagnosis and epidemiology is crucial for prevention, as rates vary globally and by patient risk.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Epidemiology
Background:
- Ventilator-associated pneumonia (VAP) is a significant nosocomial infection in intensive care units (ICUs).
- Preventing VAP is a priority due to associated morbidity, despite diagnostic controversies.
- External pressures encourage VAP reduction, with some viewing it as preventable.
Purpose of the Study:
- To highlight the importance of understanding VAP diagnostics and epidemiology.
- To emphasize the link between diagnostic methods and VAP prevalence.
- To discuss factors influencing VAP epidemiology.
Main Methods:
- Literature review on VAP epidemiology and diagnostics.
- Analysis of factors affecting VAP rates.
- Comparison of VAP incidence across different settings.
Main Results:
- VAP rates are influenced by the diagnostic approach used.
- Specific patient groups are at higher risk for VAP.
- VAP incidence appears higher internationally compared to the US.
Conclusions:
- Accurate diagnosis and epidemiological understanding are fundamental to addressing VAP.
- Patient case-mix and diagnostic strategies significantly impact VAP epidemiology.
- Global variations in VAP rates warrant further investigation.
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