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The prognostic value of obtaining a negative endoscopy in children with functional gastrointestinal disorders

Silvana Bonilla1, Deli Wang, Miguel Saps

  • 1Northwestern University, Chicago, IL, USA.

Clinical Pediatrics
|January 19, 2011
PubMed

Insights

For children with functional gastrointestinal disorders (FGIDs), a normal endoscopy does not appear to improve symptom outcomes. This finding suggests reassurance from negative endoscopy results does not significantly alter the course of FGIDs in pediatric patients.

Area of Science:

  • Pediatric Gastroenterology
  • Functional Gastrointestinal Disorders
  • Diagnostic Procedures

Background:

  • Functional gastrointestinal disorders (FGIDs) are prevalent in children, with diagnosis typically relying on the Rome criteria.
  • Endoscopies are sometimes performed in FGID cases, with the hypothesis that normal findings may provide reassurance and improve patient outcomes.

Purpose of the Study:

  • To evaluate the impact of normal endoscopic findings on the outcomes of pediatric patients diagnosed with FGIDs.

Main Methods:

  • A retrospective review of medical records for 301 patients diagnosed with abdominal pain-related FGIDs was conducted.
  • Parental completion of the Questionnaire on Pediatric Gastrointestinal Symptoms III (QPGS III) assessed symptom presence and severity at follow-up.

Main Results:

  • Overall, 62.6% of patients reported persistent abdominal pain (AP), while 37.4% were asymptomatic.
  • The prevalence of persistent AP was similar between patients who underwent endoscopy (61%) and those who did not (64%, P = .76).
  • No significant differences were observed in AP frequency, intensity, or associated child disability between the endoscopy and no-endoscopy groups.

Conclusions:

  • The findings do not support the notion that a negative endoscopy enhances outcomes for children experiencing FGIDs.
  • Reassurance from normal endoscopic results does not appear to significantly alter symptom persistence or severity in pediatric FGID patients.
Abstract

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