Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Large Intestine01:09

Large Intestine

The large intestine is divided into three main regions: the cecum, colon, and rectum. Extending from the ileocecal valve to the anus, it frames the small intestine on three sides.
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Veins of the Abdomen and Pelvis01:18

Veins of the Abdomen and Pelvis

The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
Physiology of the Gastrointestinal System III: Elimination01:26

Physiology of the Gastrointestinal System III: Elimination

The gastrointestinal elimination process involves a complex interplay of neural and hormonal mechanisms that coordinate the final waste removal from the body. This intricate operation encompasses the absorption of water and electrolytes, vital for transforming the remaining indigestible food matter into feces. The large intestine is pivotal in water and electrolyte absorption, forming feces from unabsorbed minerals, undigested food, bacteria, bile pigments, and shed epithelial cells. Essential...
Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Osimertinib plus datopotamab deruxtecan in patients with EGFR-mutated advanced NSCLC after progression on first-line osimertinib: ORCHARD.

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

ItaLynch: an ongoing Italian study to evaluate the feasibility of mainstreaming the diagnosis of Lynch syndrome in colorectal cancer patients.

ESMO gastrointestinal oncology·2026
Same author

Fetal treatment of sacrococcygeal teratoma: state of the art.

Frontiers in pediatrics·2025
Same author

Integrated fire management as an adaptation and mitigation strategy to altered fire regimes.

Communications earth & environment·2025
Same author

Corrigendum to "Under-reporting of subjective symptoms and its prognostic value: a pooled analysis of 12 cancer clinical trials": [ESMO Open 9 (2024) 102941].

ESMO open·2024
Same author

Under-reporting of subjective symptoms and its prognostic value: a pooled analysis of 12 cancer clinical trials.

ESMO open·2024

Related Experiment Video

Updated: Jun 5, 2026

Isolation of Murine Valve Endothelial Cells
09:34

Isolation of Murine Valve Endothelial Cells

Published on: August 21, 2014

Ileocaecal valve: how important is it?

S Folaranmi1, G Rakoczy, J Bruce

  • 1Department of Pediatric Surgery, Royal Manchester Children's University Hospital, Manchester, UK.

Pediatric Surgery International
|January 19, 2011
PubMed
Summary
This summary is machine-generated.

The ileocaecal valve is crucial for preventing chronic diarrhea after hemicolectomy. Preserving or reconstructing this valve is recommended, as its loss, not the removed segment, significantly impacts bowel function.

Related Experiment Videos

Last Updated: Jun 5, 2026

Isolation of Murine Valve Endothelial Cells
09:34

Isolation of Murine Valve Endothelial Cells

Published on: August 21, 2014

Area of Science:

  • Gastroenterology
  • Surgical Research
  • Pediatric Surgery

Background:

  • The ileocaecal valve (ICV) plays a vital role in gastrointestinal function.
  • Its importance in preventing complications like chronic diarrhea after bowel resection is not fully understood, especially outside of short bowel syndrome and Crohn's disease.

Purpose of the Study:

  • To investigate the functional significance of the ileocaecal valve (ICV).
  • To evaluate the impact of ICV resection versus preservation on chronic diarrhea in pediatric patients.

Main Methods:

  • Retrospective review of 123 pediatric patients undergoing hemicolectomy or ileal resection.
  • Patients were categorized into three groups: ICV resection, hemicolectomy, and terminal ileal resection.
  • Exclusion criteria included Crohn's disease, short bowel syndrome, and incomplete follow-up.

Main Results:

  • Chronic diarrhea occurred in 27% of patients with ICV resection and 26% after hemicolectomy.
  • No diarrhea was observed in patients with terminal ileal resection (0%).
  • A significant difference in diarrhea incidence was found between ICV resection/hemicolectomy groups and the ileal resection group (p < 0.05).

Conclusions:

  • Loss of the ileocaecal valve (ICV) is a significant factor contributing to chronic diarrhea post-hemicolectomy.
  • The findings suggest that preserving or reconstructing the ICV is important for maintaining normal bowel function.
  • Surgical strategies should consider ICV integrity to minimize postoperative complications.