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Updated: Jun 5, 2026

Detection of Helicobacter pylori Infection and Antibiotic Resistance via Stool Quantitative Polymerase Chain Reaction Analysis
Published on: May 16, 2025
[The evidence of Helicobacter pylori in gastric biopsy and stool samples]
1Department of Clinical Microbiology, Regional Hospital Pardubice, Pardubice, Czech Republic. eva.zalabska@nemocnice-pardubice.cz
Abstract:
In the diagnosis of Helicobacter pylori infection, it is possible to use either invasive methods when it is essential to take biopsy samples from endoscopic examination or non-invasive methods which do not require endoscopy. The invasive tests include histological examination, culture, rapid urease test and molecular methods. The non-invasive methods are serological tests, stool antigen detection (HpsAg) and respiratory tests. The article compares biopsy culture with stool antigen detection in a group of 300 patients in whom stool samples were collected simultaneously with endoscopic examination.
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