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Updated: Jun 5, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates
14:32

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates

Published on: February 27, 2016

Catalysis and mechanistic insights into sirtuin activation.

Kristin E Dittenhafer-Reed1, Jessica L Feldman, John M Denu

  • 1Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA.

Chembiochem : a European Journal of Chemical Biology
|January 19, 2011
PubMed
Summary

This review explores activators of SIRT1 (NAD(+)-dependent protein deacetylase), focusing on screening assays and catalytic mechanisms. It discusses potential therapeutic applications for metabolic and age-related diseases.

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