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Updated: Jun 5, 2026

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

Published on: May 27, 2022

[Intracytoplasmic sperm injection for obstructive azoospermia].

Qiang Du¹, Da-Lei Yang, Bo-Chen Pan

¹Center of Reproductive Medicine, Shengjing Hospital, China Medical University, Shenyang, Liaoning 110003, China. nkdoctor@sj-hospital.org

Zhonghua Nan Ke Xue = National Journal of Andrology

|January 20, 2011

Summary

This summary is machine-generated.

Intracytoplasmic sperm injection (ICSI) effectively treats obstructive azoospermia. Patients with congenital bilateral absence of vas deferens (CBAVD) experienced higher pregnancy rates with ICSI compared to other obstructive azoospermia cases.

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Vessel-Sparing Microsurgical Longitudinal Intussusception Vasoepididymostomy to Treat Epididymal Obstructive Azoospermia

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Area of Science:

Reproductive Medicine
Andrology
Infertility Treatment

Background:

Obstructive azoospermia is a significant cause of male infertility.
Intracytoplasmic sperm injection (ICSI) has emerged as a key assisted reproductive technology.
Understanding treatment outcomes in specific obstructive azoospermia subgroups is crucial.

Purpose of the Study:

To evaluate the efficacy of ICSI in treating obstructive azoospermia.
To compare ICSI outcomes between patients with congenital bilateral absence of vas deferens (CBAVD) and other causes of obstructive azoospermia.

Main Methods:

Retrospective analysis of 107 obstructive azoospermia cases treated with ICSI.
Comparison of fertilization, cleavage, and pregnancy rates.
Stratification of patients into CBAVD and non-CBAVD (inflammation/surgery-induced) groups.

Main Results:

Overall pregnancy rate was 41.4% across 107 ICSI cycles.
Patients with CBAVD achieved a significantly higher pregnancy rate (55.1%) compared to non-CBAVD patients (29.3%).
Fertilization and cleavage rates showed no significant difference between the groups.

Conclusions:

PESA or TESE combined with ICSI is effective for obstructive azoospermia.
CBAVD patients demonstrate superior pregnancy outcomes with ICSI.
Non-CBAVD causes like inflammation or surgery may negatively impact sperm quality and embryonic development potential.