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Updated: Jun 5, 2026
05:31
Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
[Allergic comorbidities in bronchial asthma, in children]
Aurica Rugină1, Tania Rusu, Ileana Ioniuc
1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină.
Summary
Allergic rhinitis and food allergies significantly increase childhood bronchial asthma prevalence and severity. These conditions, along with other allergic comorbidities, indicate that extrinsic allergic asthma is a systemic disease influenced by genetics.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
- Genetics
Context:
- Bronchial asthma is a leading chronic childhood illness.
- Allergic rhinitis is frequently associated with asthma, increasing its prevalence and severity.
- Food allergies can manifest as respiratory symptoms, particularly in IgE-mediated responses.
Purpose:
- To explore the systemic nature of extrinsic allergic bronchial asthma in children.
- To highlight the impact of allergic comorbidities on asthma presentation and severity.
- To underscore the role of genetic factors in determining clinical features.
Summary:
- Childhood bronchial asthma is strongly linked to allergic rhinitis, with prevalence rising to 60% in affected children.
- Food allergies contribute to respiratory symptoms and can be part of multisystem reactions or chronic respiratory conditions.
- Associated conditions like sinusitis, ocular allergies, and sleep apnea suggest extrinsic allergic asthma is a systemic disease.
Impact:
- Recognizing allergic bronchial asthma as a systemic condition aids in comprehensive patient management.
- Understanding the influence of comorbidities can lead to improved diagnostic and therapeutic strategies.
- Genetic predisposition plays a key role in the diverse clinical manifestations of childhood asthma.
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