Related Experiment Video
Updated: Jun 5, 2026
In situ Compressive Loading and Correlative Noninvasive Imaging of the Bone-periodontal Ligament-tooth Fibrous Joint
Published on: March 7, 2014
A 2-year prospective study on immediate loading with fluoride-modified implants in the edentulous mandible
Bruno Collaert1, Lieve Wijnen1, Hugo De Bruyn1
1Centre for Periodontology and Implantology, Leuven, Heverlee, BelgiumDepartment of Periodontology, Centre for Oral Health Sciences, Malmö University, Malmö, SwedenDepartment of Periodontology and Oral Implantology, Faculty of Medicine and Health Sciences, Ghent University, Ghent, BelgiumDepartment of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.
Immediate loading of fluoride-modified implants demonstrates high survival and success rates. This study shows minimal marginal bone loss, confirming predictability for edentulous mandibles.
Area of Science:
- Dental Implantology
- Biomaterials Science
- Oral Surgery
Background:
- Chemically modified implant surfaces enhance osseointegration.
- Fluoride-modified implants (e.g., Osseospeed®) show promise for faster bone formation.
- Long-term data on immediate loading of these implants, particularly regarding marginal bone loss, is limited.
Purpose of the Study:
- To evaluate implant survival and marginal bone level changes.
- To assess outcomes of fluoride-modified implants under immediate loading.
- To investigate the predictability of this treatment in completely edentulous mandibles over 24 months.
Main Methods:
- Prospective study of 25 patients with completely edentulous mandibles.
- Placement of five fluoride-modified implants per patient, immediately loaded.
- Measurement of marginal bone loss at 3, 6, 12, and 24 months post-surgery.
- Success criteria: <1 mm bone loss and no mobility/pain at 20 N cm torque after 24 months.
Main Results:
- 100% implant survival rate after 24 months.
- Mean marginal bone loss was minimal (0.11-0.14 mm) and stabilized after 3 months.
- No implants exceeded 1 mm bone loss; mean patient bone loss was 0.12 mm.
- Favorable probing pocket depth and bleeding index were observed.
Conclusions:
- Immediate loading of fluoride-modified implants is a predictable and successful treatment.
- High survival and success rates are achievable with minimal marginal bone loss.
- This approach offers a reliable solution for full-arch rehabilitation in the mandible.
