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Conjunctivitis due to adenovirus type 19.

J W Taylor, J W Chandler, M K Cooney

    Journal of Clinical Microbiology
    |August 1, 1978
    PubMed
    Summary

    Adenovirus type 19 (Ad19) caused an unusual conjunctivitis outbreak in Seattle. Ad19 infections led to more severe eye issues and secondary illnesses compared to other causes.

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    Area of Science:

    • Ophthalmology
    • Virology
    • Epidemiology

    Background:

    • An unusual outbreak of conjunctivitis occurred in Seattle during the summer of 1974.
    • Conjunctivitis, commonly known as pink eye, can have various causes, including viral infections.

    Purpose of the Study:

    • To identify the causative agent of the conjunctivitis outbreak in Seattle.
    • To characterize the clinical features and transmission patterns of the identified pathogen.

    Main Methods:

    • Specimen collection from referred cases for virus isolation and serological testing.
    • Analysis of clinical data including ocular pathology, visual impairment, and duration of illness.
    • Comparison of Ad19-related cases with conjunctivitis of other etiologies.

    Main Results:

    • Adenovirus type 19 (Ad19) was identified in 67% of the 42 referred cases.
    • Ad19 infections were associated with more severe ocular pathology, transient visual impairment, and prolonged illness.
    • Secondary illnesses were significantly more frequent in Ad19-infected individuals (26%) compared to other causes (5%).
    • Common symptoms included sore throat without cough or fever; no common source was identified.

    Conclusions:

    • Adenovirus type 19 was the primary cause of the 1974 Seattle conjunctivitis outbreak.
    • Ad19 infection presents with distinct clinical features, including severe ocular involvement and increased secondary illness rates.
    • The outbreak highlights the potential for Ad19 to cause significant public health concern through conjunctivitis.

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