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Related Concept Videos

Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
Classification of Illness01:17

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...

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Updated: Jun 5, 2026

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites
09:52

A Mouse Model for Pathogen-induced Chronic Inflammation at Local and Systemic Sites

Published on: August 8, 2014

[Chronic diseases. Definition and basic concept].

H Raspe1

  • 1Seniorprofessor für Bevölkerungsmedizin, Zentrum für Bevölkerungsmedizin und Versorgungsforschung, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck. heiner.raspe@uk-sh.de

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
|January 20, 2011
PubMed
Summary
This summary is machine-generated.

Chronic diseases are lifelong, multifactorial conditions impacting biological, psychic, and social health. Comprehensive assessment and collaborative goal-setting are crucial for managing this diverse patient burden.

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Area of Science:

  • Medicine
  • Public Health
  • Gerontology

Context:

  • Chronic diseases represent a significant and growing global health challenge.
  • Understanding the multifaceted nature of chronic illness is essential for effective patient care.
  • The concept of chronicity extends beyond a single diagnosis to encompass lifelong patient burden.

Purpose:

  • To highlight the diversity of chronic diseases and their lifelong implications.
  • To emphasize the need for a holistic approach to chronic disease management.
  • To differentiate between comorbidity and related conditions in chronic illness.

Summary:

  • Chronic diseases are characterized by their long-term nature and impact on biological, psychological, and social well-being.
  • Effective management requires systematic screening, assessment of comorbidities, and distinguishing them from risk factors or complications.
  • Multidisciplinary collaboration is vital for setting therapeutic goals and implementing diverse treatment strategies.

Impact:

  • Improved patient outcomes through comprehensive and individualized care plans.
  • Enhanced understanding of chronic disease complexity for healthcare professionals.
  • Facilitation of integrated care models addressing the holistic needs of patients with chronic conditions.