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Flecainide intoxication
B Levine1, D Chute, Y H Caplan
1Office of the Chief Medical Examiner, State of Maryland, Baltimore, Maryland 21201.
Journal of Analytical Toxicology
|September 1, 1990
Abstract:
A fatal case attributed to flecainide intoxication is presented. Quantitation was by capillary gas chromatography with nitrogen-phosphorus detection. The flecainide concentration in the blood was 13 mg/L as compared to a therapeutic range in serum of 0.2-1.0 mg/L. Flecainide concentrations in other specimens were as follows: bile, 160 mg/L; urine, 54 mg/L; vitreous humor, 7.4 mg/L; liver, 180 mg/kg; kidney, 74 mg/kg; and stomach contents, 120 mg.