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Urgent maxillectomy in infants for rare infantile maxillary tumors
Hazem E Amer1, Asser A Sharkawy, Ahmed Musad
1Department of Otolaryngology, Mansoura Faculty of Medicine, Gomhoria Street, Mansoura 35516, Egypt.
Insights
Surgical management of rare infant tumors, Melanotic Neuroectodermal Tumor of Infancy (MNTI) and Epithelioid Hemangioendothelioma (EHE), achieved complete tumor resection in all cases. Complete excision proved curative for these pediatric maxilla swellings.
Area of Science:
- Pediatric Oncology
- Surgical Oncology
- Maxillofacial Surgery
Background:
- Melanotic Neuroectodermal Tumor of Infancy (MNTI) and Epithelioid Hemangioendothelioma (EHE) are rare pediatric neoplasms.
- These tumors can present as slow-growing, painless swellings of the maxilla in infants.
- Early diagnosis and surgical intervention are crucial for optimal outcomes.
Purpose of the Study:
- To present surgical experience with definitive management of MNTI and EHE in infants.
- To highlight the efficacy of surgical resection for these rare pediatric tumors.
- To review the long-term outcomes of surgical intervention in a pediatric cohort.
Main Methods:
- Retrospective review of four male infants diagnosed with MNTI (n=3) or EHE (n=1).
- Preoperative imaging included CT scans and MRI.
- All patients underwent surgical intervention for tumor removal.
Main Results:
- Complete tumor resection was achieved in all four infants.
- No residual tumor or recurrence was observed post-surgery.
- The mean age of patients was 6 months (range: 2-9 months).
- No adjuvant chemotherapy or radiation therapy was required.
Conclusions:
- MNTI and EHE are rare but treatable infant tumors of the maxilla.
- Preoperative imaging is essential for surgical planning.
- Complete surgical excision is the definitive and curative treatment modality.
Objective:
The purpose of this study was to present our experience with definitive surgical management of infants with Melanotic neuroectodermal tumor of infant (MNTI) and epithelioid hemangioendothelioma (EHE).
Patients And Methods:
This study included four male infants with histologically proven MNTI (three infants) and EHE (one infant). CT scan and MRI were for taken for the patients preoperatively. Surgical intervention was used in all infants.
Results:
This study is a retrospective study that reflects our experience in the last 20 years in maxillectomy in infants. All infants were male with mean age 6 months (2-9 months). Complete resection of the tumor was achieved all infants with no residual or recurrence. Neither chemotherapy nor radiation was used in this study.
Conclusions:
MNTI and EHE are rare tumor of infant. They present as a slow painless hard swelling of the maxilla. Imaging is an essential before surgical treatment. Complete excision is curative.
