Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

Published on: August 3, 2019

Calculating gait kinematics using MR-based kinematic models.

Lennart Scheys¹, Kaat Desloovere, Arthur Spaepen

¹Medical Image Computing (Radiology - ESAT/PSI), University Hospital Leuven Campus, Gasthuisberg, Herestraat 4, B-3000 Leuven, Belgium. Lennart.scheys@uz.kuleuven.ac.be

|January 21, 2011

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A predictive simulation framework for personalised in silico gait retraining in knee osteoarthritis.

Journal of biomechanics·2026

Same author

Nutritional intake in children with cerebral palsy and typically developing peers: A comprehensive study using a novel smartphone application.

Clinical nutrition ESPEN·2026

Same author

From hip to ankle in the sagittal plane: evidence for generalized proprioceptive deficits in children with unilateral and bilateral spastic cerebral palsy through 3D motion analysis.

Disability and rehabilitation·2026

Same author

Longitudinal Trajectories of Sedentary Time and Physical Activity in Children With Cerebral Palsy: Time to Move.

Journal of physical activity & health·2026

Same author

Assessment of trunk movement and posture in spastic and dyskinetic cerebral palsy: A scoping review.

Developmental medicine and child neurology·2026

Same author

Altered gait strategies show inconsistent medial compartment unloading in varus medial knee osteoarthritis awaiting high tibial osteotomy.

Clinical biomechanics (Bristol, Avon)·2026

Same journal

Effects of auditory perturbations on recovery dynamics as a component of locomotor resilience in healthy young and older adults.

Gait & posture·2026

Same journal

Systematic analysis of success of lower limb muscle combinations in the prediction of ankle biomechanics during stair descent: Guiding input selection in sEMG-based prosthetic control.

Gait & posture·2026

Same journal

Reliability and minimal detectable change of knee mechanics during gait and squatting, using markerless motion capture in the workplace.

Gait & posture·2026

Same journal

An exploration of the association between knee confidence and knee biomechanics in people with knee osteoarthritis.

Gait & posture·2026

Same journal

A balance-weighted gait score (BWGS) reflects biomechanical and control features of gait in older adults.

Gait & posture·2026

Same journal

Incremental predictive value of spatiotemporal gait parameters beyond clinical measures for achieving independent outdoor ambulation in subacute stroke patients: A retrospective cohort study.

Gait & posture·2026

See all related articles

Subject-specific magnetic resonance (MR)-based models provide more reliable gait kinematics than generic models, especially for cerebral palsy (CP) patients. This improves accuracy in calculating hip and knee joint movements during walking.

Area of Science:

Biomechanics
Medical Imaging
Orthopedics

Background:

Generic biomechanical models are commonly used for inverse kinematics but introduce errors.
Errors stem from landmark palpation and joint coordinate system definitions.
Subject-specific models, especially MR-based ones, offer higher accuracy and reduced sensitivity to these errors.

Purpose of the Study:

To compare gait kinematics derived from rescaled generic models versus subject-specific MR-based models.
To quantify differences in hip and knee joint kinematics during gait between these modeling approaches.
To evaluate the clinical relevance of these differences in pediatric cerebral palsy (CP) patients.

Main Methods:

Calculated gait kinematics using rescaled generic models and subject-specific MR-based models.

More Related Videos

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

Published on: February 12, 2020

Related Experiment Videos

Last Updated: Jun 5, 2026

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

3D Kinematic Gait Analysis for Preclinical Studies in Rodents

Published on: August 3, 2019

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

3D Kinematic Analysis for the Functional Evaluation in the Rat Model of Sciatic Nerve Crush Injury

Published on: February 12, 2020

Included 7 pediatric CP subjects with increased femoral anteversion.

Compared results to the standard clinical data processing workflow.

Main Results:

Significant differences were observed between generic/standard workflow models and MR-based models.
Kinematic discrepancies were most prominent in sagittal and transverse planes (hip/knee flexion, hip rotation).
MR-based models demonstrated improved reliability for gait kinematics, particularly in CP patients.

Conclusions:

MR-based kinematic models enhance the reliability of gait analysis compared to generic models.
This improvement is crucial for CP subjects with bony deformities affecting joint configurations.
Despite costs, subject-specific detail in joint axis determination is essential for accurate biomechanical modeling.