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Carbon monoxide involved in modulating HCO3- secretion in rat duodenum.

Hironori Takasuka1, Shusaku Hayashi, Masafumi Koyama

  • 1Division of Pathological Sciences, Department of Pharmacology and Experimental Therapeutics, Kyoto Pharmaceutical University, Kyoto, Japan.

The Journal of Pharmacology and Experimental Therapeutics
|January 21, 2011
PubMed
Summary

Carbon monoxide (CO) stimulates duodenal bicarbonate secretion via prostaglandins. Endogenous CO, produced by heme oxygenase (HO), also plays a protective role in maintaining duodenal mucosal integrity.

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