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Late stent thrombosis after paclitaxel-eluting stent placement in a patient with essential thrombocytosis

Telat Keleş1, Nihal Akar Bayram, Tahir Durmaz

  • 1Department of Cardiology, Ankara Atatürk Education and Research Hospital, Ankara.

Turk Kardiyoloji Dernegi Arsivi : Turk Kardiyoloji Derneginin Yayin Organidir
|January 21, 2011
PubMed

Insights

Essential thrombocythemia increases the risk of late stent thrombosis after drug-eluting stent placement. Patients with this condition may not be suitable candidates for drug-eluting stents due to this risk.

Area of Science:

  • Cardiology
  • Hematology

Background:

  • Drug-eluting stents (DES) are commonly used to treat coronary artery disease.
  • Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterized by elevated platelet counts.

Observation:

  • A 51-year-old male with ET presented with acute chest pain three months after paclitaxel-eluting stent placement.
  • He was on dual antiplatelet therapy (aspirin and clopidogrel).
  • Coronary angiography revealed total occlusion at the stented site.

Findings:

  • The patient experienced late stent thrombosis, a rare but serious complication.
  • Successful balloon angioplasty restored coronary blood flow.
  • The patient's platelet count normalized post-procedure.

Implications:

  • This case highlights the potential contraindication of DES in patients with ET.
  • Careful patient selection and risk stratification are crucial for DES implantation.
  • Alternative treatment strategies may be warranted for ET patients with coronary artery disease.

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