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Related Concept Videos

Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
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Teeth01:15

Teeth

The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
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Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Tooth Anatomy01:21

Tooth Anatomy

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Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...

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Related Experiment Video

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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
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Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries

Published on: March 31, 2021

Medication caries: another form of "snacking".

B K Rubin, M Simunovic

    Canadian Family Physician Medecin De Famille Canadien
    |January 21, 2011
    PubMed
    Summary

    Children with chronic illnesses needing long-term medication face increased dental caries risk due to sucrose in medicines. Limiting sugary snacks and medications during meals is crucial for preventing tooth decay.

    Area of Science:

    • Pediatric Dentistry
    • Public Health
    • Pharmacology

    Background:

    • Dental caries prevention relies on fluoride, hygiene, and dietary control.
    • Medications containing sucrose pose a significant risk for dental caries in children with chronic illnesses.
    • Long-term medication use increases susceptibility to tooth decay complications.

    Purpose of the Study:

    • To highlight the elevated risk of dental caries in children using sucrose-containing medications.
    • To recommend strategies for mitigating caries risk associated with pediatric medication.
    • To inform healthcare providers and caregivers about medication's impact on dental health.

    Main Methods:

    • Literature review on dental caries and medication.
    • Analysis of sucrose content in common pediatric medications.

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  • Assessment of caries risk factors in chronically ill children.
  • Main Results:

    • Many pediatric medications contain high sucrose concentrations, equivalent to sweet snacks.
    • Children on long-term medication are at higher risk for caries and its complications.
    • Standard dental hygiene practices may be insufficient without medication modification.

    Conclusions:

    • Medications with sucrose should be treated as a significant cariogenic risk factor.
    • Replacing sucrose with less cariogenic sweeteners in medications is recommended.
    • Administering sucrose-containing medications with meals can minimize dental caries risk.