Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which leads...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dirty-appearing white matter in multiple sclerosis: preliminary observations of myelin phospholipid and axonal loss.

Journal of neurology·2008
Same author

Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology.

Multiple sclerosis (Houndmills, Basingstoke, England)·2007
Same author

A Phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses.

Neurology·2006
Same author

Standardized MR imaging protocol for multiple sclerosis: Consortium of MS Centers consensus guidelines.

AJNR. American journal of neuroradiology·2006
Same author

Water content and myelin water fraction in multiple sclerosis. A T2 relaxation study.

Journal of neurology·2004
Same author

The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis [RETIRED]: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology.

Neurology·2003
Same journal

Impact of virtual case conferences between primary care clinicians and an interdisciplinary chronic pain clinic.

Canadian family physician Medecin de famille canadien·2026
Same journal

Canadian family physician Medecin de famille canadien·2026
Same journal

Predictors of high-performing family medicine clinics: Prospective cohort study in Alberta.

Canadian family physician Medecin de famille canadien·2026
Same journal

Acetylsalicylic acid use for artial fibrillation and bleeding risk.

Canadian family physician Medecin de famille canadien·2026
Same journal

Clinical practice guidelines: Important tools to teach the art of medicine.

Canadian family physician Medecin de famille canadien·2026
Same journal

Paratonia in advanced dementia: Challenges and evidence-based interventions.

Canadian family physician Medecin de famille canadien·2026
See all related articles

Related Experiment Video

Updated: Jun 5, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

New perspectives in multiple sclerosis.

D W Paty

    Canadian Family Physician Medecin De Famille Canadien
    |January 21, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Multiple sclerosis (MS) is a disabling neurological disease in young adults, likely caused by genetic and environmental factors. Advances in diagnosis and new treatments offer hope for managing the condition.

    More Related Videos

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
    09:41

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

    Published on: July 19, 2019

    Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord
    10:44

    Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord

    Published on: February 22, 2015

    Related Experiment Videos

    Last Updated: Jun 5, 2026

    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
    08:51

    Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

    Published on: February 19, 2021

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
    09:41

    Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

    Published on: July 19, 2019

    Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord
    10:44

    Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord

    Published on: February 22, 2015

    Area of Science:

    • Neurology
    • Immunology
    • Genetics

    Background:

    • Multiple sclerosis (MS) is a significant neurological disorder affecting young adults.
    • The exact cause of MS remains unknown, but research points to a combination of genetic susceptibility and environmental triggers.
    • Understanding the pathogenesis of MS is crucial for developing effective treatments.

    Purpose of the Study:

    • To summarize current understanding of multiple sclerosis etiology.
    • To highlight advancements in diagnostic and monitoring techniques for MS.
    • To discuss emerging therapeutic strategies for managing MS.

    Main Methods:

    • Review of recent scientific literature on multiple sclerosis.
    • Analysis of genetic and environmental factors implicated in MS.
    • Evaluation of new diagnostic tools like magnetic resonance imaging (MRI).
    • Assessment of novel drug classes for MS treatment.

    Main Results:

    • Evidence suggests a genetic predisposition combined with an environmental trigger for MS.
    • Magnetic resonance imaging (MRI) provides valuable insights into MS pathogenesis.
    • New drug classes are emerging with the potential to slow MS progression.

    Conclusions:

    • Multiple sclerosis etiology involves complex genetic and environmental interactions.
    • Advanced imaging techniques are revolutionizing MS diagnosis and monitoring.
    • Future therapies hold promise for retarding the disease process in multiple sclerosis.