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Related Experiment Video

Updated: Jun 5, 2026

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

Published on: April 25, 2016

Glucocorticoids for croup.

Kelly F Russell¹, Yuanyuan Liang, Kathleen O'Gorman

¹Department of Pediatrics, University of Alberta, Aberhart Centre One, 11402 University Ave, Edmonton, Alberta, Canada, T6G 2J3.

The Cochrane Database of Systematic Reviews

|January 21, 2011

Summary

This summary is machine-generated.

Glucocorticoids effectively treat croup in children, reducing symptom severity and hospital stays. This systematic review confirms their benefit, leading to fewer return visits and decreased epinephrine use.

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Fecal Glucocorticoid Analysis: Non-invasive Adrenal Monitoring in Equids

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Published on: February 27, 2018

Area of Science:

Pediatric Respiratory Medicine
Evidence-Based Medicine

Background:

Croup management guidelines have evolved since 1997.
New randomized trials on glucocorticoid efficacy in croup have been published.
This review synthesizes current evidence to guide clinical practice.

Purpose of the Study:

To evaluate the effectiveness of glucocorticoids in treating children with croup.
To identify research gaps in croup management.

Main Methods:

Systematic review and meta-analysis of randomized controlled trials (RCTs).
Searched CENTRAL, MEDLINE, and EMBASE databases up to July 2010.
Included 38 RCTs with 4299 pediatric participants.

Main Results:

Glucocorticoids significantly improved croup symptom scores (Westley score) at 6 and 12 hours.
Reduced need for return visits/hospital readmissions (RR 0.5).
Decreased emergency department/hospital length of stay and epinephrine use.

Conclusions:

Dexamethasone and budesonide are effective for croup symptom relief within 6 hours.
Glucocorticoid treatment reduces hospitalizations and healthcare utilization.
Further research needed on guideline dissemination and evidence uptake.