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Updated: Jun 5, 2026

Isolation and Adoptive Transfer of High Salt Treated Antigen-presenting Dendritic Cells
Published on: March 5, 2019
Renal inflammation, autoimmunity and salt-sensitive hypertension
Bernardo Rodríguez-Iturbe1, Martha Franco, Edilia Tapia
1Renal Service, University Hospital, University of Zulia and Venezuelan Institute of Scientific Research-Zulia, Maracaibo, Estado Zulia, Venezuela. brodrigueziturbe@gmail.com
Abstract:
1. The present article reviews the role of immune-competent cells infiltrating the kidney and their association with oxidative stress and renal angiotensin activity in the development of salt-sensitive hypertension. 2. We discuss changes in the pressure-natriuresis relationship resulting from renal inflammation and its improvement resulting from immunosuppressive treatment. 3. The potential role of T-cell-driven reactivity in sustaining the renal inflammation is examined in the light of accumulating evidence of autoimmune mechanisms in experimental and clinical hypertension.
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