Tn2008 is a major vehicle carrying bla(OXA-23) in Acinetobacter baumannii from China
Xiaohui Wang1, Zhiyong Zong, Xiaoju Lü
1Center of Infectious Diseases, West China Hospital, Sichuan University, Chengdu 610041, China.
Diagnostic Microbiology and Infectious Disease
|January 22, 2011
Abstract:
bla(OXA-23) and bla(OXA-66) were detected in 49 Acinetobacter baumannii isolates. These isolates were assigned to 7 subtypes by enterobacterial repetitive intergenic consensus polymerase chain reaction and 7 representative isolates were of ST92 or ST75. In most cases, the ISAba1-bla(OXA-23)-ATPaseΔ structure was identical to Tn2008. The 16-bp sequence at the left end of Tn2008 resembled the inverted repeat of ISAba1, suggesting that ISAba1 might have utilized an alternative boundary to mobilize bla(OXA-23).
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