Related Experiment Video
Updated: Jun 5, 2026

06:53
Cell Population Analyses During Skin Carcinogenesis
Published on: August 21, 2013
Keratin 15-positive stem cells give rise to basal cell carcinomas in irradiated Ptch1(+/-) mice
John T Seykora1, George Cotsarelis
1Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA.
Cancer Cell
|January 22, 2011
Abstract:
The cell of origin for basal cell carcinoma (BCC) remains controversial. In this issue of Cancer Cell, Wang et al. provide strong evidence that BCC arise from hair follicle stem cells.

![Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F60445.jpg&w=3840&q=50)