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Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
Published on: September 22, 2023
[Allergic fungal rhinosinusitis caused by Curvularia sp.]
Verónica C Alvarez1, Liliana Guelfand, Juan Carlos Pidone
1Sección de Microbiología, Hospital Naval Cirujano Mayor Dr. Pedro Mallo, Buenos Aires, Argentina. vcalvarez32@hotmail.com
Abstract:
Allergic fungal rhinosinusitis is a benign and non-invasive sinusal disease related to a hypersensitivity reaction to fungal antigens. This process can cause tissue edema with chronic inflammatory disturbances of the respiratory mucosa. We present the case of a 17 year-old immunocompetent male, with history of seasonal allergic rhinosinusitis, nasal polyps and previous surgery for mucocele of the frontal sinus. Sticky material was removed in the last surgery that revealed pigmented and septed filaments on direct examination, and yielded Curvularia on Sabouraud dextrose agar. After a course of amphotericin B, treatment was switched to itraconazole, with good tolerance and favorable clinical outcome.
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