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Antimicrobial resistance in Salmonella enterica serovar Enteritidis in Morocco

Farida Ohmani1, Khadija Khedid, Saad Britel

  • 1Laboratory of Medical Bacteriology, National Institute of Hygiene 27, Avenue Ibn Batouta, BP 769, Rabat, Morocco. farida.ohmani@gmail.com

Journal of Infection in Developing Countries
|January 22, 2011
PubMed
Abstract

Insights

Salmonella Enteritidis in Morocco shows low overall antimicrobial resistance. However, resistance to nalidixic acid is common, with many resistant strains also showing reduced susceptibility to ciprofloxacin.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Salmonella enterica serovar Enteritidis is a significant cause of human gastrointestinal infections globally.
  • Understanding antimicrobial resistance patterns is crucial for effective treatment and control.

Purpose of the Study:

  • To determine the antimicrobial susceptibilities of Salmonella Enteritidis isolates from human sources in Morocco.
  • To assess resistance trends between 2000 and 2008.

Main Methods:

  • Disk diffusion method was used to test susceptibility to seven antibiotics.
  • Minimal inhibitory concentration (MIC) of ciprofloxacin was determined for nalidixic acid-resistant isolates using E-test strips.

Main Results:

  • 42% of isolates exhibited resistance to at least one antimicrobial agent.
  • Nalidixic acid resistance was most prevalent (36%), followed by ampicillin (5%), tetracycline (4%), and trimethoprim/sulfamethoxazole (1%).
  • Of the nalidixic acid-resistant isolates, 76% showed reduced susceptibility to ciprofloxacin.

Conclusions:

  • While overall resistance rates are low, nalidixic acid resistance in Salmonella Enteritidis is a significant concern in Morocco.
  • Continuous surveillance of antibiotic resistance is essential for public health interventions.

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