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Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos
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Studying Mitotic Checkpoint by Illustrating Dynamic Kinetochore Protein Behavior and Chromosome Motion in Living Drosophila Syncytial Embryos

Published on: June 14, 2012

Spindly switch controls anaphase: spindly and RZZ functions in chromosome attachment and mitotic checkpoint control

Marin Barisic1, Stephan Geley

  • 1Division of Molecular Pathophysiology, Innsbruck Medical University, Innsbruck, Austria.

Cell Cycle (Georgetown, Tex.)
|January 22, 2011
PubMed

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The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
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