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Related Concept Videos

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...

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Related Experiment Video

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Pre-Implantation Genetic Testing for Aneuploidy on a Semiconductor Based Next-Generation Sequencing Platform
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Non-invasive prenatal testing.

B C McGillivray

    Canadian Family Physician Medecin De Famille Canadien
    |January 22, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Non-invasive pregnancy assessments like ultrasound and blood tests help identify risks. These tools aid clinicians in adjusting prenatal care when needed, but their limitations must be understood.

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    FISH for Pre-implantation Genetic Diagnosis

    Published on: February 23, 2011

    Area of Science:

    • Obstetrics and Gynecology
    • Maternal-Fetal Medicine
    • Diagnostic Imaging

    Background:

    • Routine prenatal care aims to monitor pregnancy health.
    • Identifying high-risk pregnancies is crucial for timely intervention.
    • Non-invasive methods offer potential for improved risk assessment.

    Purpose of the Study:

    • To review non-invasive modalities for assessing ongoing pregnancies.
    • To highlight their role in identifying risk factors.
    • To emphasize appropriate clinical application and awareness of limitations.

    Main Methods:

    • Review of established non-invasive prenatal assessment techniques.
    • Inclusion of pedigree analysis, maternal serum alphafetoprotein screening, fetal ultrasonography, and Doppler ultrasound.
    • Discussion of clinical indications and limitations.

    Main Results:

    • Non-invasive methods can aid in identifying pregnancies requiring modified care.
    • Specific modalities like ultrasound and Doppler offer valuable insights.
    • Effective use depends on clinical context and understanding of test performance.

    Conclusions:

    • Non-invasive assessment tools are valuable adjuncts in prenatal care.
    • Clinicians should utilize these methods judiciously based on indications.
    • Awareness of the limitations of each modality is essential for accurate risk identification.