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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...
Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis01:25

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

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Related Experiment Video

Updated: Jun 5, 2026

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
08:13

Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)

Published on: January 7, 2018

Gestational diabetes: a review.

C Levitt

    Canadian Family Physician Medecin De Famille Canadien
    |January 22, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Gestational diabetes mellitus (GDM) screening using universal methods yields many false positives, leading to unnecessary interventions. Alternative approaches to GDM diagnosis and management are explored.

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    A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
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    A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

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    Related Experiment Videos

    Last Updated: Jun 5, 2026

    Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)
    08:13

    Study of In Vivo Glucose Metabolism in High-fat Diet-fed Mice Using Oral Glucose Tolerance Test (OGTT) and Insulin Tolerance Test (ITT)

    Published on: January 7, 2018

    Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo
    10:35

    Extracellular Glucose Depletion as an Indirect Measure of Glucose Uptake in Cells and Tissues Ex Vivo

    Published on: April 6, 2022

    A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
    10:03

    A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

    Published on: February 28, 2013

    Area of Science:

    • Obstetrics and Gynecology
    • Endocrinology
    • Public Health

    Background:

    • Gestational diabetes mellitus (GDM) is a frequent pregnancy complication.
    • Incidence of GDM varies significantly (1.6%–13%) based on diagnostic criteria and screening methods.
    • Current universal screening protocols often result in false positives.

    Purpose of the Study:

    • To critically examine the literature supporting universal screening for GDM.
    • To present recommendations from the Second International Workshop-Conference on Gestational Diabetes Mellitus.
    • To discuss alternative strategies for GDM screening, diagnosis, and management.

    Main Methods:

    • Literature review of studies on universal GDM screening.
    • Analysis of diagnostic criteria and their impact on incidence rates.
    • Examination of the risks and benefits associated with various screening and diagnostic approaches.

    Main Results:

    • The glucose-challenge screening test frequently produces false-positive results.
    • Diagnosis of GDM can lead to "high-risk" labeling and extensive interventions.
    • The study reviews current literature on GDM screening and control.

    Conclusions:

    • The basis for universal GDM screening practices requires careful examination.
    • Alternative screening and diagnostic methods may offer a more accurate approach.
    • A balanced consideration of risks and benefits is crucial for GDM management.