Related Experiment Video
Updated: Jun 5, 2026

06:42
Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
Breast cancer in developing countries: opportunities for improved survival
Lawrence N Shulman1, Walter Willett, Amy Sievers
1Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.
Journal of Oncology
|January 22, 2011
Summary
Breast cancer survival has improved due to advances, but early detection and treatment offer significant opportunities, especially in low-income countries. Increased awareness and accessible primary care are key for better outcomes.
Area of Science:
- Oncology
- Public Health
- Epidemiology
Background:
- Breast cancer survival in the USA has seen continuous improvement over six decades.
- Advances in mammography, surgery, and adjuvant therapies are credited for survival gains.
- Significant survival improvements occurred even before these technological advancements.
Purpose of the Study:
- To highlight opportunities for early breast cancer detection and treatment in low- and middle-income countries.
- To suggest strategies for improving breast cancer survival in resource-limited settings.
- To emphasize the role of awareness and accessible healthcare in managing breast cancer.
Main Methods:
- The study analyzes historical trends in breast cancer survival data from the USA.
- It infers the impact of early detection and accessible treatment on survival rates.
- It reviews the components of successful breast cancer management in various healthcare settings.
Main Results:
- Substantial improvements in breast cancer survival were observed in the USA prior to widespread advanced technologies.
- These historical trends suggest that early detection and treatment are critical for survival.
- Low- and middle-income countries can achieve significant survival improvements through accessible primary care and awareness.
Conclusions:
- Improving breast cancer survival in low- and middle-income countries is achievable through increased awareness and accessible primary care.
- A strong primary care system, free from economic and cultural barriers, is essential.
- Effective referral systems for basic surgical and hormonal treatments are crucial for successful outcomes.
Related Concept Videos
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Targeted Cancer Therapies
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
There are several types of targeted therapies against specific...
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
