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Related Experiment Video

Updated: Jun 5, 2026

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts

Published on: January 29, 2018

Birth weight in children with birth defects.

Sonia Montes-Núñez¹, Dora Virginia Chávez-Corral, Sandra Reza-López

¹Unidad de Investigación Médica en Epidemiología Clínica Chihuahua, Ave. Colón 1003, Colonia Obrera, Chihuahua, Mexico.

Birth Defects Research. Part A, Clinical and Molecular Teratology

|January 22, 2011

Summary

Newborns with birth defects in Mexico are more likely to be small for their gestational age. Specific birth defects, such as those affecting the digestive or genital systems, are linked to lower birth weights, indicating a need for nutritional considerations.

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Published on: May 17, 2024

Area of Science:

Pediatrics
Public Health
Medical Genetics

Background:

Birth defects (BDs) represent a significant public health concern in Mexico.
Identifying associations between BDs and neonatal outcomes is crucial for improving infant health.

Purpose of the Study:

To determine the frequency of newborns born small for gestational age (SGA) among those with birth defects.
To investigate the relationship between specific types of BDs and SGA status.

Main Methods:

A cross-sectional study was conducted involving newborns from hospitals within the Mexican Institute of Social Security in Chihuahua, Mexico.
Newborns were classified based on the presence or absence of BDs and their weight percentile using regional birth weight standards.

Main Results:

A total of 263 newborns with BDs and 64,626 without BDs were analyzed.
Newborns with BDs exhibited a higher proportion of being small for gestational age (20%) compared to those without BDs (9%).
Specific BDs were associated with significant reductions in birth weight, including digestive system defects (-210g), genital organ defects (-440g), chromosomal abnormalities (-230g), and musculoskeletal system defects (-289g).

Conclusions:

A higher prevalence of newborns small for gestational age was observed in those with birth defects.
Certain birth defects are more strongly associated with impaired birth weight than others.
Clinical management of newborns with congenital defects and low birth weight should include assessment for and management of potential nutritional deficiencies.