Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Prevention of Further Absorption of Poison

Prevention of Further Absorption of Poison

In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...

Autophagic Cell Death

Autophagic Cell Death

Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and pro-apoptotic...

Phagocytosis of Apoptotic Cells

Phagocytosis of Apoptotic Cells

Cells undergoing apoptosis form apoptotic bodies that must be removed immediately to prevent inflammation, autoimmune diseases, and necrosis. Phagocytosis is carried out by professional phagocytes such as macrophages or immature dendritic cells. Non-professional phagocytes such as epithelial cells and fibroblasts also take part in this process; however, they are not as effective as professional phagocytes.
Normal cells contain receptors that prevent them from being recognized by phagocytes.

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterase Agents: Poisoning and Treatment

Anticholinesterases, also known as cholinesterase inhibitors, work by blocking the breakdown of acetylcholine, leading to its accumulation in the synaptic cleft. This accumulation indirectly enhances both muscarinic and nicotinic actions. These agents are classified as reversible or irreversible based on their mechanism of action.
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...

The Stanford Prison Experiment

The Stanford Prison Experiment

The famous and controversial Stanford Prison Experiment, conducted by social psychologist Philip Zimbardo and his colleagues at Stanford University, demonstrated the power of social roles, social norms, and scripts.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Yellow meconium.

Forensic science, medicine, and pathology·2024

Same author

Penetrating skull stab.

Forensic science, medicine, and pathology·2024

Same author

DNA transfer to firearms in alternative realistic handling scenarios.

Forensic science international. Genetics·2020

Same author

All mixed up?-genotype change after stem cell transplantation impeded verification of 21-year-old semen sample-a case report.

International journal of legal medicine·2019

Same author

[Death after explosion of an "empty" acetone barrel].

Archiv fur Kriminologie·2013

Same author

Effect of non-protein components on the degradability of proteins.

Biotechnology advances·2007

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

A β-glucuronidase (GUS) Based Cell Death Assay

A β-glucuronidase (GUS) Based Cell Death Assay

Published on: May 6, 2011

[Suicide with a manipulated hand grenade].

Johanna Preuss-Wössner¹, Jürgen Kroll

¹Institut für Rechtsmedizin des Universitätsklinikums Schleswig-Holstein.

Archiv Fur Kriminologie

|January 25, 2011

Summary

This summary is machine-generated.

This case study details a rare civilian suicide involving a modified hand grenade. The explosive charge was improvised from readily available fire-cracker powder, not standard trinitrotoluene (TNT).

More Related Videos

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine

A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine

Published on: October 27, 2015

Related Experiment Videos

Last Updated: Jun 5, 2026

A β-glucuronidase (GUS) Based Cell Death Assay

A β-glucuronidase (GUS) Based Cell Death Assay

Published on: May 6, 2011

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Setup and Execution of the Rapid Cycle Deliberate Practice Death Notification Curriculum

Published on: August 5, 2020

A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine

A Simple Device to Rapidly Prepare Whole Mounts of the Mouse Intestine

Published on: October 27, 2015

Area of Science:

Forensic Pathology
Toxicology
Ballistics

Background:

Civilian explosion injuries are infrequent.
This report details an unusual suicide case involving a manipulated hand grenade.

Observation:

The victim sustained massive soot blackening, singeing, and splinter injuries.
Evidence suggested the use of black powder from fire-crackers instead of standard trinitrotoluene (TNT).
The victim was found in a sitting position, having detonated the grenade with his right hand.

Findings:

The grenade was modified using parts from multiple devices and commercially available black powder.
The victim died from a fractured femur and liver lacerations.
High blood alcohol content (2.5 per mille) and numerous unlicensed weapons in the residence indicated suicide under severe intoxication.

Implications:

This case highlights the potential for improvised explosive devices using accessible materials.
Forensic analysis is crucial in distinguishing between standard and manipulated explosive devices.
The findings underscore the importance of regulating access to materials that can be used to create improvised explosive devices.