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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

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Metabolomics and human nutrition.

Sandy Primrose¹, John Draper, Rachel Elsom

¹Prosciagen Consulting, High Wycombe, UK.

The British Journal of Nutrition

|January 25, 2011

Summary

Metabolomics research successfully identified novel biomarkers for food intake, offering new ways to track diet. Future work will validate these biomarkers for public health nutrition surveys.

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Area of Science:

Human Nutrition
Metabolomics
Biomarker Discovery

Background:

Workshop convened by the UK Food Standards Agency to discuss metabolomics in human nutrition research.
Focused on reviewing progress, identifying challenges, and setting future research priorities.

Framework:

Utilizing metabolomics technologies for human nutrition research.
Exploring the application of metabolomics in public health nutrition research and surveys.

Implementation:

Studies demonstrated the identification of novel food intake biomarkers not predictable from food composition data.
Proof-of-principle established for using metabolomics to develop new dietary intake biomarkers.

Implications:

Next steps include biomarker validation and developing rapid assays for public health relevance.
Potential to enhance population cohort studies and dietary surveys with new biomarker tools.