Related Experiment Video
Updated: Jun 5, 2026

Thin-layer Chromatographic (TLC) Separations and Bioassays of Plant Extracts to Identify Antimicrobial Compounds
Published on: March 27, 2014
Impurity profiling of pharmaceuticals by thin-layer chromatography
K Ferenczi-Fodor1, Z Végh, B Renger
1Gedeon Richter Plc., P.O.B. 27, H-1475 Budapest, Hungary. k.fodor@richter.hu
Abstract:
Although there is a tendency in current pharmacopoeias for favouring HPLC, thin-layer chromatography (TLC) is still a very popular and frequently used analytical method in the pharmaceutical industry. This paper highlights the possibilities of this method in the different areas of pharmaceutical analysis like in-process and intermediate control, illustrated by impurity testing of active ingredients and final products, as well as its application in pharmaceutical research and development, based on some examples reported mainly in the last five years.
More Related Videos
06:14Estimating the Yield of Compounds on the TLC Plate via the Blue-LED Illumination Technique
Published on: October 6, 2022
10:33Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
Published on: October 26, 2015
Related Concept Videos
Ion-Exchange Chromatography
High-Performance Liquid Chromatography: Introduction
In HPLC, two phases play a critical role in the separation process:
Thin-Layer Chromatography (TLC): Overview
To begin the analysis, a mixture of compounds is spotted on the starting line on the TLC plate using a thin capillary. The bottom of the...
Affinity Chromatography
High-Performance Liquid Chromatography: Instrumentation
Types Of Column Chromatography
Gel Filtration Chromatography
When the...