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Published on: October 17, 2013
Serial changes of hemodynamic performance with Medtronic Hall valve in aortic position
Yang Hyun Cho1, Dong Seop Jeong, Pyo Won Park
1Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Insights
The Medtronic Hall valve in aortic position can show increased pressure gradients over time, particularly after double valve replacement or with smaller valve sizes. This finding is crucial for long-term hemodynamic performance monitoring.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Clinical Cardiology
Background:
- The Medtronic Hall valve is a mechanical prosthetic used in aortic valve replacement (AVR).
- Long-term hemodynamic performance of prosthetic valves is critical for patient outcomes.
Purpose of the Study:
- To evaluate the long-term hemodynamic performance of the Medtronic Hall valve in the aortic position.
- To analyze serial changes in echocardiographic outcomes following AVR with this valve.
Main Methods:
- Retrospective study of 117 patients undergoing AVR with Medtronic Hall valve (1997-2004).
- Patients were divided into isolated AVR and double valve replacement groups.
- Serial echocardiographic data were analyzed over a mean follow-up of 93.7 months.
Main Results:
- 11.1% of patients experienced an aortic transprosthetic mean pressure gradient increase >15 mm Hg.
- Double valve replacement and small valve size (20 mm) predicted this gradient increase.
- Adverse cardiac event-free survival at 10 years was significantly better in the isolated AVR group (80.1% vs. 53.8%).
Conclusions:
- The transprosthetic mean pressure gradient of the Medtronic Hall valve frequently increases over time in the aortic position.
- This gradient increase is more prevalent in patients who underwent double valve replacement, especially with small valve sizes.
- These findings highlight the importance of monitoring hemodynamic changes in patients with Medtronic Hall valves.
Background:
The aim of this study was to evaluate the long-term hemodynamic performance of the Medtronic Hall valve by analyzing serial changes in echocardiographic outcomes in aortic position.
Methods:
One hundred seventeen patients who underwent aortic valve replacement (AVR) using the Medtronic Hall valve between August 1997 and January 2004 were retrospectively studied. Fifty-five patients underwent isolated AVR (AVR group), and 62 patients underwent AVR and mitral valve replacement (double valve replacement group). Mean age was 51.2 ± 10.4 years (range, 26 to 67 years), and mean follow-up duration was 93.7 ± 25.6 months (913.6 patient-years; range, 17 to 140 months). Serial echocardiographic data were analyzed.
Results:
Overall mortality was 12.8% (15 of 117), but no early mortality occurred. A greater than 15 mm Hg increment of aortic transprosthetic mean pressure gradient at last follow-up occurred in 13 patients (11.1%). Redo AVR was performed in 7 patients, 6 of whom had subaortic pannus ingrowths. Group cumulative survival rates at 10 years were similar (90.4%, AVR group versus 88.4%, double valve replacement group; p = 0.580), but the AVR group showed better adverse cardiac event-free survival at 10 years (80.1% versus 53.8%; p = 0.025). Multivariate analysis showed that double valve replacement and a small-sized valve (20 mm) significantly predicted the increment of aortic transprosthetic mean pressure gradient at last follow up greater than 15 mm Hg (p = 0.013; odds ratio, 13.9; p = 0.019; odds ratio, 4.2, respectively).
Conclusions:
The transprosthetic mean pressure gradient of the Medtronic Hall valve in the aortic position frequently increased as a function of time, and this increase was more common in patients who had undergone double valve replacement, especially in those implanted with a small valve.
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