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Pyroptosis: macrophage suicide exposes hidden invaders.

Igor E Brodsky1, Ruslan Medzhitov

  • 1Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA. igor.brodsky@yale.edu

Current Biology : CB
|January 25, 2011
PubMed
Summary

Caspase-1 is crucial for fighting infections by triggering pyroptosis, a type of cell death, and releasing inflammatory signals. New research emphasizes pyroptosis

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