Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Factors Affecting Illness01:18

Factors Affecting Illness

When a person's physical, emotional, intellectual, social development or spiritual functioning is compromised, this deviation from a healthy normal state is called illness. Illness creates stress that in turn harms individuals. Irritation, anger, denial, hopelessness, and fear are behavioral and emotional changes an individual experiences in the phases of illness. A variety of factors influence a person's health and well-being.
For instance, risk factors are connected to illness, disability,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

External validation of the European and American equations for calculating cardiovascular risk in a Spanish working population.

Revista clinica espanola·2021
Same author

High cardiovascular risk in Spanish workers.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2010
Same author

Pharmacological treatment of acute stress disorder with propranolol and hypnotics.

Actas espanolas de psiquiatria·2007
Same author

[Immunotherapy in asthma].

Revista clinica espanola·2003
Same author

[Captopril in single doses in the treatment mild-moderated arterial hypertension].

Revista clinica espanola·1990
Same author

[Pleural effusion associated with a neoplasm. Review of 274 cases].

Revista clinica espanola·1984

Related Experiment Video

Updated: Jun 5, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

[Modulating variables of work disability in depressive disorders].

C Catalina Romero1, M Cabrera Sierra, J C Sainz Gutiérrez

  • 1Ibermutuamur (Mutua de accidentes de trabajo y enfermedades profesionales n.° 274), Madrid, España. carloscatalina@ibermutuamur.es

Revista De Calidad Asistencial : Organo De La Sociedad Espanola De Calidad Asistencial
|January 25, 2011
PubMed
Summary

Depression significantly prolongs sickness absence, averaging 120 days. Female sex, older age, lower education, and specific referral patterns are linked to longer work disability duration.

More Related Videos

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
05:28

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

Related Experiment Videos

Last Updated: Jun 5, 2026

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
06:55

An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents

Published on: December 2, 2015

A New Method for Inducing a Depression-Like Behavior in Rats
07:57

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice
05:28

A Chronic Immobilization Stress Protocol for Inducing Depression-Like Behavior in Mice

Published on: May 15, 2019

Area of Science:

  • Occupational Health
  • Psychiatry
  • Public Health

Background:

  • Depressive disorders are a leading cause of work disability.
  • Understanding factors influencing sickness absence duration is crucial for effective management.

Purpose of the Study:

  • To quantify sickness absence duration in unipolar depression.
  • To identify demographic, job-related, and clinical predictors of temporary work disability length in depressive disorders.

Main Methods:

  • Prospective observational study of 1,292 subjects diagnosed with depressive disorders claiming sick leave.
  • Descriptive analyses of sickness absence duration.
  • Bivariate (median test) and multivariate (logistic regression) analyses were conducted.

Main Results:

  • The mean duration of sickness absence episodes was 120 days.
  • Female sex, older age, lower educational level, self-employed/unemployed status, and referral to both psychiatrist and psychologist were significantly associated with longer sick leave.

Conclusions:

  • Depression is strongly associated with prolonged work disability and high absenteeism.
  • There is a need to enhance functional ability assessment, promotion, treatment, and referral for depressed patients.