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[Intracranial ependymomas: retrospective study of 16 cases]
M Houjami1, S Sahraoui, N Benchakroun
1Centre d'Oncologie, CHU Ibn Rochd, Casablanca, Maroc. mhoujami@yahoo.fr
Purpose:
To report the epidemiological, clinical aspects and therapeutic results of intracranial ependymomas in Morocco.
Patients And Methods:
Our retrospective study concerned 16 cases of intracranial ependymomas, treated from January 1995 to December 2002 at the radiotherapy department of Ibn Rochd Hospital of Casablanca, Morocco.
Results:
The average age was 15 years and complete surgery was possible in two cases. All the patients received cranial radiotherapy, combined with chemotherapy in six cases. Overall survival and progression-free survival at 5 years were respectively 50% and 31%. Eleven patients had local recurrence after an average period of 21 months. Progression-free survival at 5 years was better if complete resection: 100% vs. 28.6% in cases of incomplete resection, and depending on the histological type with 50% for classic ependymomas and 16.6% for anaplastic.
Conclusion:
Ependymomas are rare tumors and complete resection is the standard treatment followed by postoperative radiotherapy. The place of chemotherapy remains to be defined.
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