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Development of an optical imaging platform for functional imaging of small animals using wide-field excitation

Vivek Venugopal1, Jin Chen, Xavier Intes

  • 1Department of Biomedical Engineering, Rensselaer Polytechnic Institute,
110 8th Street Troy NY 12180, United States.

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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...