The changes in submandibular gland size and function following chorda tympani section

Area of Science:

• Otolaryngology
• Surgical Anatomy
• Glandular Physiology

Background:

• The chorda tympani nerve plays a role in submandibular gland function.
• Chronic otitis media surgery may involve chorda tympani sectioning.
• Understanding the impact on salivary glands is crucial for patient care.

Purpose of the Study:

• To evaluate the effects of chorda tympani section on submandibular gland size and function.
• To assess changes in the early and late postoperative periods.
• To utilize a multimodal assessment approach.

Main Methods:

• 102 patients undergoing tympanoplasty or mastoidectomy for chronic otitis media were studied.
• Submandibular gland size was measured using ultrasonography.
• Scintigraphy assessed gland perfusion index (PI), uptake ratio, and excretion fraction.
• Saliva biochemistry (sodium, potassium, amylase, pH, etc.) was analyzed.

Main Results:

• Submandibular gland volume on the operated side was significantly smaller at 6 months post-surgery.
• Perfusion index (PI) significantly decreased at both 7 days and 6 months post-surgery.
• Saliva secretion and gland excretion fraction showed significant decreases in the early postoperative period.

Conclusions:

• Chorda tympani section leads to a decrease in submandibular gland volume in the late postoperative period.
• The procedure also reduces saliva secretion and perfusion index, impacting gland function.
• This study highlights the functional consequences of chorda tympani nerve sacrifice.