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[Colonic Crohn's disease complicated with peripheral neuropathy]
F Chaoui1, H Hellal, M Balamane
1Service de Gastroentérologie, CHU Ain Taya, Boumerdes, Algérie.
Gastroenterologie Clinique Et Biologique
|January 1, 1990
Summary
Crohn
Area of Science:
- Gastroenterology and Neurology
- Neuroimmunology
Background:
- Crohn's disease (CD) is a chronic inflammatory bowel disease.
- Peripheral neuropathy (PN) is an uncommon complication of CD.
- Vitamin B12 deficiency and metronidazole are common causes of PN in CD patients.
Observation:
- A patient presented with severe axonal polyneuropathy.
- The patient had a diagnosis of Crohn's disease.
- Vitamin B12 levels were normal, and metronidazole treatment was not administered.
Findings:
- The patient's polyneuropathy was not attributable to vitamin B12 deficiency or metronidazole.
- This case highlights a rare extra-digestive manifestation of Crohn's disease.
- Suggests a potential direct link between Crohn's disease and axonal polyneuropathy.
Implications:
- This case expands the understanding of neurological complications in Crohn's disease.
- Further research is needed to elucidate the pathogenic mechanisms.
- Highlights the importance of considering non-standard causes of PN in CD patients.