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Therapy of refractory, recurrent heart rejection with multiple courses of OKT3
W H Frist1, E B Gerhardt, W H Merrill
1Department of Cardiac and Thoracic Surgery, Vanderbilt University Medical Center, Nashville, Tenn.
The Journal of Heart Transplantation
|November 1, 1990
Abstract:
The treatment for recurrent cardiac allograft rejection refractory to conventional immunotherapy is retransplantation. When retransplantation is not possible, alternative approaches must be undertaken. This report reviews the successful management of persistently recurring rejection using five serial 14-day courses of OKT3 in a 35-year-old man after two heart transplantations.