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Updated: Jun 5, 2026

Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
Visual acuity and nystagmus following strabismus surgery in patients with oculocutaneous albinism
Victor M Villegas1, Lilliam Díaz, Andres Emanuelli
1University of Puerto Rico School of Medicine, Department of Ophthalmology, San Juan, Puerto Rico.
Objective:
To evaluate the effect of strabismus surgery on nystagmus and visual acuity in patients with oculocutaneous albinism.
Methods:
We conducted a non-concurrent retrospective study of 13 Puerto Rican patients with all types of oculocutaneous albinism who underwent strabismus surgery. Patients underwent genetic linkage analysis to reach a final oculocutaneous albinism classification prior to surgery. Strabismus surgery was modified by under-correction of 0.5 mm in each muscle from the standard Marshall Parks' measurements in all patients.
Results:
Six of the 13 patients with oculocutaneous reported an improved best corrected visual acuity after surgery. Two of the 13 patients with oculocutaneous had no nystagmus following strabismus surgery. All patients were orthotropic following surgery.
Conclusion:
Strabismus surgical undercorrection may be of benefit in patients with oculocutaneous albinism.
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