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Regression Toward the Mean01:52

Regression Toward the Mean

Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Apparent Weight01:09

Apparent Weight

True weight is the measure of the gravitational force acting on an object. However, if the object accelerates, its measured weight is different from its true weight. Similar observations can be made when the object is submerged in water. An object's weight in water is its apparent weight, which is equal to the difference between its true weight and the buoyant forces.
Consider a person standing on a bathroom scale inside an elevator. If the scale is accurate at rest, its reading equals the...
Mass and Weight01:19

Mass and Weight

Mass and weight are often used interchangeably in everyday conversation. For example,  medical records often show our weight in kilograms, but never in the correct units of newtons. In physics, however, there is an important distinction. Weight is the pull of the Earth on an object. It depends on the distance from the center of the Earth. Weight dramatically varies if we leave the Earth's surface, unlike mass, which does not vary with location. On the Moon, for example, the acceleration due to...
Mass and Weight01:19

Mass and Weight

Mass and weight are often used interchangeably in everyday conversation. For example,  medical records often show our weight in kilograms, but never in the correct units of newtons. In physics, however, there is an important distinction. Weight is the pull of the Earth on an object. It depends on the distance from the center of the Earth. Weight dramatically varies if we leave the Earth's surface, unlike mass, which does not vary with location. On the Moon, for example, the acceleration due to...
Apparent Weight and the Earth's Rotation01:28

Apparent Weight and the Earth's Rotation

Since all objects on the Earth's surface move through a circle every 24 hours, there must be a net centripetal force on each object, directed towards the center of that circle. The points of the north and south poles are the only exception to this rule.
For an object on the Earth's equator, the net centripetal force that accounts for its rotation is the Earth's pull towards its center, or the weight minus the normal force that prevents it from piercing into the Earth's surface. This force,...
Clearance Models: Physiological Models01:09

Clearance Models: Physiological Models

Drug clearance is a critical pharmacokinetic process involving the irreversible removal of drugs from the body through various organs over a specified time period. Physiological models are indispensable in determining organ-specific clearance, defined by the proportion of the drug eliminated per unit of time from the organ's blood volume.
The organ's clearance rate depends on the blood flow to the organ and the extraction ratio (E). The extraction ratio describes the organ's proficiency in drug...

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Related Experiment Video

Updated: Jun 5, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Weight science: evaluating the evidence for a paradigm shift.

Linda Bacon1, Lucy Aphramor

  • 1University of California, Davis, USA. linda@lindabacon.org

Nutrition Journal
|January 26, 2011
PubMed
Summary

The Health at Every Size (HAES) approach offers weight-neutral health benefits, outperforming traditional weight loss methods. HAES improves physiological and psychosocial health without the harms of dieting.

Area of Science:

  • Public Health
  • Behavioral Medicine
  • Health Psychology

Background:

  • Current guidelines advocate weight loss for overweight/obese individuals via lifestyle changes.
  • This approach often fails long-term, leading to adverse effects like eating disorders and weight stigma.
  • Concerns about ineffectiveness and harm prompt re-evaluation of weight-centric health strategies.

Purpose of the Study:

  • To evaluate the evidence supporting a shift from weight-focused interventions to a Health at Every Size (HAES) paradigm.
  • To compare the efficacy and safety of HAES with traditional weight loss treatments.

Main Methods:

  • Review of randomized controlled trials and scientific literature.
  • Analysis of physiological, health behavior, and psychosocial outcomes.

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Control of Eating Behavior Using a Novel Feedback System
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Control of Eating Behavior Using a Novel Feedback System

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Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging
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Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Related Experiment Videos

Last Updated: Jun 5, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Control of Eating Behavior Using a Novel Feedback System
04:48

Control of Eating Behavior Using a Novel Feedback System

Published on: May 8, 2018

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging
06:48

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Main Results:

  • Health at Every Size (HAES) interventions show significant improvements in blood pressure, lipids, eating habits, and self-esteem.
  • HAES demonstrates superior or equivalent health outcomes compared to weight loss treatments.
  • HAES avoids the negative contraindications associated with weight-focused approaches.

Conclusions:

  • A paradigm shift towards HAES is justified by robust evidence.
  • Weight-neutral health strategies offer a more effective and ethical approach to improving well-being.