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Updated: Jun 5, 2026

Laparoscopic Left Hemihepatectomy Combined with Caudate Lobe Resection
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Sublobar versus lobar resection: current status.

Chaitan K Narsule1, Michael I Ebright, Hiran C Fernando

  • 1Department of Cardiothoracic Surgery, Boston University School of Medicine, Boston,MA 02118, USA.

Cancer Journal (Sudbury, Mass.)
|January 26, 2011
PubMed
Summary
This summary is machine-generated.

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Sublobar resection may be a viable option for early-stage non-small cell lung cancer, offering comparable outcomes to lobectomy for select patients. Careful surgical technique and potential adjuvant brachytherapy are key to improving results.

Area of Science:

  • Thoracic Surgery
  • Surgical Oncology
  • Pulmonary Medicine

Background:

  • Lobectomy is the standard treatment for early-stage non-small cell lung cancer (NSCLC) due to concerns about local recurrence with sublobar resection.
  • Sublobar resection is generally reserved for high-risk patients with operable lung cancer.

Purpose of the Study:

  • To review the current evidence on sublobar resection for early-stage lung cancer.
  • To evaluate factors influencing outcomes, including tumor characteristics and surgical techniques.

Main Methods:

  • Review of recent studies comparing lobectomy and sublobar resection for early-stage NSCLC.
  • Analysis of technical aspects of sublobar resection, such as segmentectomy and wide wedge resection.
  • Inclusion of data on adjuvant brachytherapy and pulmonary function preservation.

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Main Results:

  • Recent studies suggest comparable recurrence and survival rates between lobectomy and sublobar resection for small, stage I lung cancers.
  • Technical modifications like segmentectomy or wide wedge resection, and the addition of brachytherapy, can improve sublobar resection outcomes.
  • Sublobar resection offers potential for better preservation of pulmonary function.

Conclusions:

  • Sublobar resection is increasingly considered for early-stage NSCLC, even in good-risk patients.
  • Tumor size, specific sublobar resection technique, and adjuvant brachytherapy are critical factors.
  • Preservation of pulmonary function is a significant advantage of sublobar resection.