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Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:

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Related Experiment Video

Updated: Jun 5, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Screening for dementia in family practice.

W W Weston

    Canadian Family Physician Medecin De Famille Canadien
    |January 26, 2011
    PubMed
    Summary

    Screening older adults with the Mini Mental State Examination (MMSE) did not identify new dementia cases in this teaching practice. The study questions the routine use of MMSE for dementia screening in primary care settings.

    Area of Science:

    • Geriatrics
    • Neurology
    • Primary Care Medicine

    Background:

    • Dementia prevalence in patients over 65 was 5.6% before screening.
    • The Mini Mental State Examination (MMSE) is a common cognitive screening tool.

    Purpose of the Study:

    • To evaluate the utility of the MMSE in identifying previously undiagnosed dementia in a primary care setting.
    • To assess the impact of MMSE screening on clinical practice and patient management.

    Main Methods:

    • A prospective study involving 90% of patients over 65 in a university-affiliated teaching practice.
    • Cognitive screening using the MMSE over a six-month period.
    • Comparison of MMSE findings with existing clinical documentation of dementia.

    Main Results:

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    • The MMSE identified no new cases of dementia; all identified patients were already known to physicians.
    • The screening tool failed to detect one case of clinical dementia within the practice.
    • No new, treatable conditions were discovered through MMSE screening.

    Conclusions:

    • The MMSE demonstrated limited value in this primary care setting for identifying new dementia cases.
    • Routine MMSE screening may not be beneficial for dementia detection when clinical assessment is already in place.
    • Further research is needed to determine the optimal screening strategies for dementia in primary care.