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Related Experiment Video

Updated: Jun 5, 2026

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

Published on: November 9, 2017

Hyperreflexic Guillain-Barré syndrome.

Neeraj N Baheti¹, Davis Manuel, Pranav D Shinde

¹Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India.

Annals of Indian Academy of Neurology

|January 26, 2011

Summary

Guillain-Barré syndrome (GBS), an autoimmune disorder, typically presents with weakness and absent reflexes. This report highlights rare cases in India with preserved or heightened reflexes, urging physicians not to overlook this variant.

Keywords:

AMAN Guillain-Barré syndrome autoimmune polyradiculoneuropathy

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Terminal H-reflex Measurements in Mice

Terminal H-reflex Measurements in Mice

Published on: June 16, 2022

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A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments

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Published on: November 9, 2017

Terminal H-reflex Measurements in Mice

Terminal H-reflex Measurements in Mice

Published on: June 16, 2022

Area of Science:

Neurology
Immunology
Neuroscience

Background:

Guillain-Barré syndrome (GBS) is an acute autoimmune polyradiculoneuropathy characterized by progressive motor weakness and areflexia.
While reflex abnormalities are documented in GBS variants globally, they are considered uncommon in the Indian subcontinent.

Observation:

This case report details two instances of GBS in the Indian subcontinent exhibiting reflex preservation and hyperreflexia.
These cases present a rare clinical manifestation of the axonal variant of GBS.

Findings:

The findings underscore that hyperreflexia, though infrequent, can occur in GBS, even in populations where it is not commonly reported.
The pathophysiology and management of this hyperreflexic variant are discussed.

Implications:

Physicians and neurologists in training should be aware of this rare hyperreflexic variant of GBS to ensure accurate diagnosis and timely management.
Recognizing atypical presentations of GBS is crucial for effective patient care and neurological training.