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Degenerative cervical spondylolisthesis: a systematic review
Sheng-Dan Jiang1, Lei-Sheng Jiang, Li-Yang Dai
1Department of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, 200092 Shanghai, China.
Insights
Degenerative cervical spondylolisthesis, often overlooked, presents with neck pain, radiculopathy, and myelopathy. Surgical intervention is considered for instability or spinal cord compression.
Area of Science:
- Spine surgery
- Neurology
- Radiology
Background:
- Degenerative cervical spondylolisthesis (DCS) is less studied than lumbar spondylolisthesis.
- DCS may be more prevalent than previously recognized.
Purpose of the Study:
- To systematically review DCS to inform treatment guidelines.
- To analyze the clinical presentation, causes, and management of DCS.
Main Methods:
- Systematic literature review of English articles (1947-2010).
- Focused on radiological examination and management of DCS.
Main Results:
- 102 patients with DCS experienced neck pain (51%), radiculopathy (22.5%), and myelopathy (63.7%).
- Most common levels affected were C3/4 (46%) and C4/5 (49.4%).
- Disc degeneration and facet hypertrophy were primary causes; 46.3% showed segmental instability.
Conclusions:
- Further prospective studies are needed for definitive management strategies.
- Surgery is indicated for radiologically proven DCS with instability or spinal cord compression.
Purpose:
Degenerative cervical spondylolisthesis has received insufficient attention, in contrast to degenerative lumbar spondylolisthesis. In fact, degenerative cervical spondylolisthesis may be more common than previously thought.
Methods:
In order to provide appropriate guidelines for the treatment of degenerative cervical spondylolisthesis, a systematic review of degenerative cervical spondylolisthesis was performed. An English literature search from January 1947 to November 2010 was completed with reference to radiological examination and management of degenerative cervical spondylolisthesis.
Results:
Of 102 patients with degenerative cervical spondylolisthesis, 52 patients (51%) had neck or occipital pain, 23 patients (22.5%) were referred with radiculopathy and 65 patients (63.7%) presented with myelopathy or myeloradiculopathy. Degenerative cervical spondylolisthesis was most common in C3/4 and C4/5, occurring in 81 patients at C3/4 (46%) and 87 at C4/5 (49.4%). Disc degeneration and facet hypertrophy were the main causes of this clinical entity. Of 123 patients, 57 (46.3%) were found to have segmental instability as shown by flexion-extension lateral radiographs. There are two classification systems for degenerative cervical spondylolisthesis. Surgery was indicated in patients who had radiologically proven cervical spondylolisthesis with instability and/or spinal cord compression.
Conclusion:
Prospective studies should be designed in the future to draw a more reliable conclusion about the management of degenerative cervical spondylolisthesis.
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