Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Surface Appendages of Archaea01:23

Surface Appendages of Archaea

Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
Flagella and Motility in Bacteria01:18

Flagella and Motility in Bacteria

Flagella are specialized, thread-like structures that extend from a bacteria's cell envelope. They play a crucial role in motility and chemotaxis. Their structural organization and functioning exemplify sophisticated biological engineering, enabling bacterial survival and adaptability in diverse environments.Structure of the FlagellumA bacterial flagellum consists of three key components: the filament, the hook, and basal body. The filament, a long, helical structure composed of repeating...
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Generation of Straight or Branched Actin Filaments01:14

Generation of Straight or Branched Actin Filaments

The straight or branched structure formation of actin filaments is controlled by nucleating proteins such as the formins and Arp2/3 complex. Formin-mediated assembly results in straight filaments, whereas Arp2/3 protein complex-mediated assembly results in branched actin filaments.
Arp2/3 Complex
Arp2/3 complex is a seven-subunit complex consisting of two proteins similar to actin- Arp2 and Arp3, and five other subunits that help keep Arp2 and Arp3 inactive. When required, the complex is...
Microtubules in Cell Motility01:24

Microtubules in Cell Motility

Microtubules are thick hollow cylindrical proteins that help form the cytoskeleton. Microtubules have varied roles in the cell. These filaments help form cellular appendages like cilia and flagella, which are responsible for locomotion. The cilia arise from basal bodies, separated from the main body by a membrane-like structure forming the transition zone. This zone is the gate for the entry of lipids and proteins, creating a unique composition of lipids and proteins in the ciliary membrane and...
Spindle Assembly02:50

Spindle Assembly

Spindle assembly occurs through three, often coexisting, pathways – the centrosome-mediated pathway, the chromatin-mediated pathway, and the microtubule-mediated pathway – collectively contributing to form a robust spindle apparatus.
In most cells, centrosomes are the primary microtubule nucleation centers. In the centrosome-mediated pathway, the G2-prophase transition triggers centrosome maturation and increased microtubule nucleation. Progressive nucleation results in a microtubule array...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multilayered cell envelope of a member of the Chloroflexota offers an anchoring platform for the archaellum.

Frontiers in microbiology·2026
Same author

CsmR controls both, motility and cell shape, in Haloferax volcanii.

PLoS genetics·2026
Same author

A conserved oscillatory system that positions the divisome in Archaea.

bioRxiv : the preprint server for biology·2026
Same author

Indigenous actinomycetes of the Himalaya: current knowledge and a bioinformatics perspective on plant growth-promoting and cold-tolerance traits.

Archives of microbiology·2026
Same author

S-Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea.

The FEBS journal·2026
Same author

Regulation of YAP activity by nuclear G-actin binding.

Nucleic acids research·2026

Related Experiment Video

Updated: Jun 5, 2026

Biophysical Characterization of Flagellar Motor Functions
06:08

Biophysical Characterization of Flagellar Motor Functions

Published on: January 18, 2017

Assembly and function of the archaeal flagellum.

Abhrajyoti Ghosh1, Sonja-Verena Albers

  • 1Molecular Biology of Archaea, Max Planck Institute for Terrestrial Microbiology, Karl-von-Frisch-Strasse 10, 35043 Marburg, Germany.

Biochemical Society Transactions
|January 27, 2011
PubMed
Summary

Archaeal flagella, crucial for motility, share structural similarities with bacterial type IV pili. Researchers identified key protein interactions, like FlaJ with FlaI, aiding in understanding archaeal flagellar assembly and evolution.

More Related Videos

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series
07:59

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series

Published on: May 10, 2020

Reconstitution of Actin-Based Motility with Commercially Available Proteins
08:40

Reconstitution of Actin-Based Motility with Commercially Available Proteins

Published on: October 28, 2022

Related Experiment Videos

Last Updated: Jun 5, 2026

Biophysical Characterization of Flagellar Motor Functions
06:08

Biophysical Characterization of Flagellar Motor Functions

Published on: January 18, 2017

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series
07:59

Investigating Flagella-Driven Motility in Escherichia coli by Applying Three Established Techniques in a Series

Published on: May 10, 2020

Reconstitution of Actin-Based Motility with Commercially Available Proteins
08:40

Reconstitution of Actin-Based Motility with Commercially Available Proteins

Published on: October 28, 2022

Area of Science:

  • Microbiology
  • Molecular Biology
  • Evolutionary Biology

Background:

  • Motility is essential for prokaryotes, with both bacteria and archaea utilizing flagella for swimming.
  • Despite serving a similar function, archaeal and bacterial flagella exhibit distinct structures.
  • Archaeal flagella show structural resemblances to bacterial type IV pili, not bacterial flagella.

Purpose of the Study:

  • To investigate the molecular mechanisms and components involved in archaeal flagellar assembly.
  • To identify conserved protein interactions within the archaeal flagellar system.
  • To elucidate the evolutionary relationship between archaeal flagella and bacterial type IV pili.

Main Methods:

  • Computational analysis of conserved protein regions.
  • Identification of protein-protein interactions within the flagellar assembly machinery.
  • Comparative analysis of flagellar components across archaeal subkingdoms.

Main Results:

  • Conserved charged loop regions in the archaeal flagellar protein FlaJ were identified.
  • These FlaJ loops are predicted to interact with the assembly ATPase FlaI.
  • Significant variation in FlaJ loops was observed between Euryarchaeota and Crenarchaeota.

Conclusions:

  • The identified interactions provide insights into the mechanics of archaeal flagellar assembly.
  • Understanding these interactions can clarify the evolutionary links to bacterial type IV pilus systems.
  • Further research into the assembly pathway and interaction map is crucial.