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Updated: Jun 5, 2026

A Rat Model of Compound Acne
Published on: November 1, 2024
Reticulated acanthoma with apocrine differentiation
Juan Carlos-Hiromi López1, Gulnara Taldibaeva, Katja Sperhake
1Department of Pathology, Universidad Nacional de Colombia, Bogotá, Colombia. jchiromi@hotmail.com
Abstract:
Reticulated acanthoma with apocrine differentiation (RAAD) represents a rare variant of adnexal neoplasm first described by Ackerman et al. in 1998. It consists of cords and columns of adnexal keratinocytes that form a reticulated pattern. Variable signs of apocrine, sebaceous and follicular differentiation may be present. Since 1998, no further cases of this condition have been published. We report on a lesion excised from the leg of a 46-year-old man, which displayed histopathological features diagnostic of RAAD. Criteria for diagnosis and differential diagnoses are discussed.
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