Related Experiment Videos
[Clinical analysis of Streptococcus faecalis septicemia in children]
1Szpitala Dzieciecego Specjalistycznego Zespołu Opieki Zdrowotnej nad Matka i Dzieckiem w Wałbrzychu.
Insights
Streptococcus faecalis sepsis in infants presents similarly to other Gram-positive sepsis, with significant drug resistance. This study analyzed 59 infant cases, revealing a 10.2% mortality rate.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neonatal Care
Background:
- Streptococcus faecalis (now Enterococcus faecalis) is a notable cause of sepsis in infants.
- Understanding the clinical characteristics and resistance patterns of this pathogen is crucial for effective treatment.
Purpose of the Study:
- To analyze the clinical features, drug resistance, and outcomes of Streptococcus faecalis sepsis in infants.
- To identify risk factors and complications associated with this infection in a vulnerable population.
Main Methods:
- Retrospective clinical analysis of 59 infant cases (1-5 months old) with Streptococcus faecalis sepsis.
- Characterization of isolated bacterial strains for antimicrobial resistance, particularly to penicillin and its derivatives.
- Review of clinical presentations, complications (e.g., meningitis, intrauterine infection), and mortality.
Main Results:
- Isolated Streptococcus faecalis strains exhibited significant drug resistance, especially to penicillin.
- Clinical presentation was largely similar to other Gram-positive sepsis.
- Meningitis occurred in 20% of cases; intrauterine infection was observed in about one-third of neonates.
- The overall mortality rate for Streptococcus faecalis sepsis in this cohort was 10.2%.
Conclusions:
- Streptococcus faecalis sepsis in infants poses a significant threat, characterized by drug resistance and potential for severe complications like meningitis.
- Early diagnosis and appropriate antibiotic selection are critical, considering the observed resistance patterns.
- The findings underscore the importance of monitoring antimicrobial resistance in neonatal and pediatric intensive care units.
Abstract:
The clinical analysis of 59 cases of Streptococcus faecalis sepsis in infants aged 1 to 5 months has been presented. Streptococcus faecalis strains isolated from the blood were characterized by drug resistance especially against penicillin or its derivatives. The clinical picture of the Streptococcus faecalis sepsis in a majority of cases is similar to that of other Gram-positive sepsis. Meningitis, first of all purulent, was noted in twenty percent of infected children. About one third of neonates with the Streptococcus faecalis sepsis showed intrauterine infection. The mortality index in children with the Streptococcus faecalis sepsis was equal to 10.2%.