Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...

Acute Respiratory Failure-V

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube through...

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Significant Published Articles in 2025 for Pharmacy Nutrition Support Practice.

Hospital pharmacy·2026

Same author

Propofol-induced hypertriglyceridemia in critically ill trauma patients requiring nutrition therapy: A descriptive cohort study.

JPEN. Journal of parenteral and enteral nutrition·2026

Same author

Evaluation of NPH Insulin Dosing Interval for Critically Ill Hyperglycemic Trauma Patients During Continuous Enteral Nutrition: A Pilot Study.

Nutrients·2025

Same author

Significant Published Articles in 2024 for Pharmacy Nutrition Support Practice.

Hospital pharmacy·2025

Same author

Estimating measured creatinine clearance for critically ill trauma patients with presumed normal kidney function.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·2025

Same author

Outpatient diabetes management influences glycemic control for critically ill patients during nutrition support: A retrospective observational study.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition·2024

Search research articles

Related Experiment Video

Updated: Jun 5, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Optimal caloric intake for critically ill patients: first, do no harm.

Roland N Dickerson¹

¹University of Tennessee-Memphis, Memphis, TN 38136, USA. rdickerson@uthsc.edu

Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition

|January 27, 2011

Summary

Accurately determining energy needs for critically ill patients is challenging. Overfeeding or underfeeding can lead to adverse outcomes, necessitating careful nutrition management and further research into optimal caloric intake.

Related Experiment Videos

Last Updated: Jun 5, 2026

Improving IV Insulin Administration in a Community Hospital

Improving IV Insulin Administration in a Community Hospital

Published on: June 11, 2012

Area of Science:

Critical Care Medicine
Clinical Nutrition
Metabolic Support

Background:

Accurate estimation of energy requirements in critically ill patients remains a significant clinical challenge.
Current methods for determining caloric needs are often imprecise and may lead to overestimation or underestimation.
Both overfeeding and inadequate nutrition support are linked to adverse clinical outcomes in this patient population.

Purpose of the Study:

To review key literature on the estimation of energy requirements in critically ill patients.
To discuss the implications of "permissive underfeeding" versus aggressive feeding strategies.
To highlight the need for further research to define optimal nutrition targets.

Main Methods:

Literature review of pivotal papers, including Krishnan et al. (2003).
Analysis of studies supporting or refuting current feeding practices.
Synthesis of evidence regarding complications of overfeeding and underfeeding.

Main Results:

No single method for calculating energy needs is universally precise or unbiased for all critically ill patients.
Overfeeding can result in complications like hyperglycemia and gastric intolerance, potentially worsening clinical outcomes.
Inadequate nutrition is also associated with poor clinical outcomes, emphasizing the need for optimized delivery.

Conclusions:

Optimal nutrition support for critically ill patients requires balancing caloric delivery to avoid complications of overfeeding and underfeeding.
Further research is essential to identify the minimum nutrition required for therapeutic benefit and the threshold beyond which additional intake provides no further advantage.
The concept of "permissive underfeeding" warrants continued investigation in clinical practice.