Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Chronic Pharyngitis01:23

Chronic Pharyngitis

Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
Disorders of Leukocytes01:27

Disorders of Leukocytes

Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An approach to somatization in family medicine.

Canadian family physician Medecin de famille canadien·2011
Same author

The orientation of medical students to total health care.

Canadian family physician Medecin de famille canadien·2010
Same author

[Not Available].

Canadian family physician Medecin de famille canadien·2010
Same author

The Hospital Bed and the General Practitioner.

Canadian Medical Association journal·2010
Same author

Prescription data.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2001
Same author

Alberta's Bill 11: will trade tribunals set domestic health policy?

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2001
Same journal

Impact of virtual case conferences between primary care clinicians and an interdisciplinary chronic pain clinic.

Canadian family physician Medecin de famille canadien·2026
Same journal

Canadian family physician Medecin de famille canadien·2026
Same journal

Predictors of high-performing family medicine clinics: Prospective cohort study in Alberta.

Canadian family physician Medecin de famille canadien·2026
Same journal

Acetylsalicylic acid use for artial fibrillation and bleeding risk.

Canadian family physician Medecin de famille canadien·2026
Same journal

Clinical practice guidelines: Important tools to teach the art of medicine.

Canadian family physician Medecin de famille canadien·2026
Same journal

Paratonia in advanced dementia: Challenges and evidence-based interventions.

Canadian family physician Medecin de famille canadien·2026
See all related articles

Related Experiment Video

Updated: Jun 5, 2026

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

Chronic mononucleosis syndrome.

S E Shortt, E R Haynes

    Canadian Family Physician Medecin De Famille Canadien
    |January 27, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Chronic mononucleosis can cause debilitating illness with vague symptoms, making diagnosis challenging. This review examines clinical and laboratory features, offering diagnostic guidelines for this complex condition.

    More Related Videos

    An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
    09:43

    An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection

    Published on: March 30, 2018

    Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
    07:38

    Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

    Published on: June 14, 2020

    Related Experiment Videos

    Last Updated: Jun 5, 2026

    Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
    08:44

    Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

    Published on: September 7, 2022

    An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
    09:43

    An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection

    Published on: March 30, 2018

    Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue
    07:38

    Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

    Published on: June 14, 2020

    Area of Science:

    • Infectious Diseases
    • Internal Medicine
    • Clinical Diagnostics

    Background:

    • Debilitating illnesses with vague symptoms pose diagnostic challenges.
    • Minimal physical examination and laboratory findings complicate patient assessment.
    • Chronic mononucleosis is a condition that can present with such nonspecific manifestations.

    Purpose of the Study:

    • To present a case of chronic mononucleosis.
    • To review the clinical and laboratory features of chronic mononucleosis.
    • To suggest diagnostic guidelines for chronic mononucleosis.

    Main Methods:

    • Case report presentation.
    • Literature review of chronic mononucleosis.
    • Analysis of four recent studies on the syndrome.

    Main Results:

    • Chronic mononucleosis can present with debilitating, nonspecific symptoms.
    • Diagnostic findings may be minimal in routine examinations.
    • Literature review highlights key clinical and laboratory indicators.

    Conclusions:

    • Accurate diagnosis of chronic mononucleosis requires careful consideration of subtle findings.
    • Diagnostic guidelines are proposed to aid physicians.
    • Further research may refine diagnostic criteria for this syndrome.